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Internal Quality Control (IQC)
Monitoring Test System Precision/Reproducibility
- Carried out daily, providing real-time performance assessment.
- No interlaboratory performance comparison without an additional peer group reporting program.
- Useful for detecting sudden or gradual shifts in performance.
- IQC samples should be manufactured with a matrix which is as close to the patient sample as possible.
External Quality Assurance (EQA)
Monitoring Test System Accuracy
- Carried out less frequently (generally once per month), providing a retrospective assessment of performance.
- Results are compared to labs using the same instrument/methos type providing an indication of any test system bias.
- Effective in detecting more complex problems, such as calibration issues.
- EQA samples should be manufactured with a matrix which is as close to the patient sample as possible.